Potassium Permanganate → HCID 86732657, compound

HRID 523443Notes

Reaction equation

HRID 523443 reaction equation
[C:1]1([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[CH:6]=[CH:5][C:4]([N:7]2[CH2:20][C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[C:13]3[CH:12]=[C:11]([C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=4)[CH:10]=[CH:9][C:8]2=3)=[CH:3][CH:2]=1.[Mn]([O-])(=O)(=O)=[O:34].[K+]>ClCCl>[C:1]1([C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=2)[CH:2]=[CH:3][C:4]([N:7]2[C:20](=[O:34])[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[C:13]3[CH:12]=[C:11]([C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=4)[CH:10]=[CH:9][C:8]2=3)=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 516875Potassium PermanganateHCID 86732658HCID 86732658, compound

Product 1

HCID 86732657HCID 86732657, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

16 g (0.039 mol) of 5-biphenyl-4-yl-2-phenyl-5,6-dihydrophenanthridine are dissolved in 300 ml of dichloromethane. and 62.13 g (0.393 mol) of potassium permanganate are added in portions to this solution, and the mixture is stirred at room temperature for two days. After this time, the remaining potassium permanganate is filtered off, the solution is evaporated and purified by chromatography (eluent: heptane/dichloromethane, 5:1). The residue is recrystallised from n-heptane. The yield is 14 g (88%).

Workup

  1. filtrationAfter this time, the remaining potassium permanganate is filtered off
  2. customthe solution is evaporated
  3. custompurified by chromatography (eluent: heptane/dichloromethane, 5:1)
  4. customThe residue is recrystallised from n-heptane

Sources & evidence

ORD record
ord-31973f8dcf494c93aa247e6f54e72513
Source dataset
uspto-grants-2016_05
Patent number
US09337430B2

Reaction notes

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