Triethylamine → HCID 135532118, compound

Participants

Reaction Steps

2-Methylsulfanyl-5,6,7,8-tetrahydro-3H-quinazolin-4-one (100 mg; 0.51 mmol), phenylpiperazin-1-ylmethanone hydrochloride (115.5 mg; 0.51 mmol) and triethylamine (141.3 μl; 1.02 mmol) are reacted in isoamyl alcohol (1 ml) in accordance with the procedure for Example 9 (reaction time 6 h) and worked up. The crystals obtained after purification by column chromatography are dissolved in acetonitrile and water and freeze-dried; yield: 47 mg (27%), crystals;

Provenance & Evidence