HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86606159, compound → Pramlintide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86606159 | HCID 86606159 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Phosphate | HCID 1061 | — |
| Solvent | Citrate | HCID 31348 | — |
| Product | Pramlintide | HCID 70691388 | — |
Reaction Steps
Pramlintide acetate was dissolved in H2O at 2 mg/mL with either a 10 mM citrate buffer, pH 4 or 10 mM phosphate buffer, pH 7. These solutions were lyophilized to dryness (>1% residual moisture) using a conservative cycle and reconstituted to various nominal concentrations in DMSO. Solubility was measured by visual inspection for clarity and turbidity via A630.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09339545B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-e1799e77c8aa486da4fe7d7a6ac82674 |
| Source note | uspto-grants-2016_05 |