Ethyl Acetate → HCID 23391440, compound

Participants

Reaction Conditions

Reaction Steps

Pure 7 (1.2 g, 3.9 mmol) was dissolved in TFA (15 mL) under nitrogen. A trace amount of MEHQ was added to the mixture and the reaction was stirred for 3 hours at 55° C. Completion of the reaction was confirmed by TLC (EtOAc/Hex/TFA: 60:40:0.1% (v/v), Rf: 0.38). The reaction mixture was purified on a silica gel column (EtOAc/Hex, 3/2). 0.6 g (65% yield) 8 was obtained as yellow oil.

Provenance & Evidence