HuagongsheHuagongshe Chemistry Print Report · For research reference only
Alanine methyl ester hydrochloride → (7-Isopropoxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Alanine methyl ester hydrochloride | HCID 2733257 | — |
| Reactant | 1-Chloro-4-hydroxy-7-isopropoxy-isoquinoline-3-carboxylic acid | HCID 53870439 | — |
| Product | (7-Isopropoxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino-propionic acid | HCID 86595459 | — |
Reaction Steps
Analogously to Example A-56, 0.040 g of 7-isopropoxy-1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid were allowed to react with 0.020 g of L-Alanine methyl ester hydrochloride to give, after hydrolysis of the intermediate ester, 0.047 g of a white solid: MS-(−)-ion, M−1=353.1 amu.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09339527B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-e5d5ffafe29f4e0aa6329397e34a7c71 |
| Source note | uspto-grants-2016_05 |