Trimethyl orthoformate → HCID 86660795, compound

Participants

Reaction Steps

A mixture of 3-aminopyridine (7.14 g, 0.076 mol) and trimethyl orthoformate (40 mL) was refluxed for approximately 60 hr. To the cooled reaction mixture was added water (50 mL) and extracted with ethyl acetate (3×50 mL). The combined organic extracts were washed with brine and dried with MgSO4. The suspension was filtered and concentrated to yield the 3-methoxyiminopyridine as a white solid (9.3 g, 90%).

Provenance & Evidence