HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 84657894, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 53493300 | HCID 53493300 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 84657894 | HCID 84657894 | — |
Reaction Steps
To 1.0 g (5.9 mmol) 2-(2-fluoro-3-methoxy-phenyl)-ethylamine and 0.66 mL (8.9 mmol) formaldehyde (37% solution in water) in 10 mL DCM are added slowly 0.91 mL (12 mmol) TFA and the resulting mixture is stirred at r.t. over night. The reaction mixture is purified by HPLC (ACN/H2O/NH4OH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09340510B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-67116bbd12ee42f7be71e471981bcf75 |
| Source note | uspto-grants-2016_05 |