HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3,5,6-Tetramethylbenzenesulphonyl chloride → HCID 46203049, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3,5,6-Tetramethylbenzenesulphonyl chloride | HCID 143740 | — |
| Reactant | 5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-piperidin-4-yl-2,4-dihydro-3H-pyrazol-3-one hydrochloride | HCID 66616406 | — |
| Product | HCID 46203049 | HCID 46203049 | — |
Reaction Steps
The title compound is prepared analogously as described for GP1 using 5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-(piperidin-4-yl)-2,4-dihydro-3H-pyrazol-3-one hydrochloride (compound B1*HCl) and 2,3,5,6-tetramethylbenzenesulfonyl chloride as starting compounds. The crude product is purified by crystallization from methanol to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09340522B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-4efb033bffe94dacba9e9883fe6ee7e8 |
| Source note | uspto-grants-2016_05 |