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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 524177Generated: November 1, 2026

1,6-Naphthyridine-5-carboxylic acid → HCID 46204653, compound

https://huagongshe.com/reaction/524177

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,6-Naphthyridine-5-carboxylic acidHCID 12549437—
Reactant5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-piperidin-4-yl-2,4-dihydro-3H-pyrazol-3-one hydrochlorideHCID 66616406—
ProductHCID 46204653HCID 46204653—

Reaction Steps

The title compound is prepared analogously as described for GP2-WU2 using 5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-(piperidin-4-yl)-2,4-dihydro-3H-pyrazol-3-one (compound B1) and 1,6-naphthyridine-5-carboxylic acid as starting compounds. The crude product is purified by chromatography (silica gel and DCM/methanol=95:5) to yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09340522B2
Source datasetuspto-grants-2016_05
ORD IDord-9786449840514e608656d4ddf5d6cefa
Source noteuspto-grants-2016_05