HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-ethoxybenzoyl Chloride → HCID 46206279, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-ethoxybenzoyl Chloride | HCID 2769417 | — |
| Reactant | 5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-piperidin-4-yl-2,4-dihydro-3H-pyrazol-3-one hydrochloride | HCID 66616406 | — |
| Product | HCID 46206279 | HCID 46206279 | — |
Reaction Steps
The title compound is prepared analogously as described for GP1 using 5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-(piperidin-4-yl)-2,4-dihydro-3H-pyrazol-3-one hydrochloride (compound B1*HCl) and 3-ethoxybenzoyl chloride as starting compounds. The crude product is purified by column chromatography (silica gel and EA) and crystallization of the product containing fractions from EA and diethyl ether to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09340522B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-dda1e9d8c19e4b45bea0f8156af97d95 |
| Source note | uspto-grants-2016_05 |