Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 524212Generated: October 31, 2026

5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-piperidin-4-yl-2,4-dihydro-3H-pyrazol-3-one hydrochloride → HCID 46206958, compound

https://huagongshe.com/reaction/524212

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-piperidin-4-yl-2,4-dihydro-3H-pyrazol-3-one hydrochlorideHCID 66616406—
ReactantHCID 86657435HCID 86657435—
ProductHCID 46206958HCID 46206958—

Reaction Steps

The title compound is prepared analogously as described for GP1 using 5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-(piperidin-4-yl)-2,4-dihydro-3H-pyrazol-3-one hydrochloride (compound B1*HCl) and 5-(benzyloxy)-2-chlorobenzoyl chloride (compound F3) as starting compounds. The crude product is purified by crystallization from EA and diethyl ether to yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09340522B2
Source datasetuspto-grants-2016_05
ORD IDord-fe241eb7dc2c4043a4fb6e7ffd038d1f
Source noteuspto-grants-2016_05