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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 524257Generated: November 1, 2026

2-Naphthoic acid → HCID 67365511, compound

https://huagongshe.com/reaction/524257

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Naphthoic acidHCID 7123—
Reactant5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-piperidin-4-yl-2,4-dihydro-3H-pyrazol-3-one hydrochlorideHCID 66616406—
ProductHCID 67365511HCID 67365511—

Reaction Steps

The title compound is prepared analogously as described for GP2-WU2 using 5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-(piperidin-4-yl)-2,4-dihydro-3H-pyrazol-3-one (compound B1) and naphthalene-2-carboxylic acid as starting compounds. The crude product is purified by chromatography (amino phase silica gel and DCM) and by crystallization from diethyl ether to yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09340522B2
Source datasetuspto-grants-2016_05
ORD IDord-ec0588cd5fe4402894c681a3d5c18aef
Source noteuspto-grants-2016_05