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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 524263Generated: October 29, 2026

3-(Dimethylamino)benzoic acid → HCID 67364099, compound

https://huagongshe.com/reaction/524263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Dimethylamino)benzoic acidHCID 66837—
Reactant5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-piperidin-4-yl-2,4-dihydro-3H-pyrazol-3-one hydrochlorideHCID 66616406—
ProductHCID 67364099HCID 67364099—

Reaction Steps

The title compound is prepared analogously as described for GP2-WU2 using 5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-(piperidin-4-yl)-2,4-dihydro-3H-pyrazol-3-one (compound B1) and 3-(dimethylamino)benzoic acid as starting compounds. The crude product is purified by chromatography (amino phase silica gel and DCM) and by crystallization from DCM and diethyl ether to yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09340522B2
Source datasetuspto-grants-2016_05
ORD IDord-88cb0bcc4a604719bfcd07d8a009920b
Source noteuspto-grants-2016_05