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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 524286Generated: October 29, 2026

2,3-Difluorobenzoyl chloride → HCID 67364627, compound

https://huagongshe.com/reaction/524286

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Difluorobenzoyl chlorideHCID 519549—
Reactant5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-piperidin-4-yl-2,4-dihydro-3H-pyrazol-3-one hydrochlorideHCID 66616406—
ProductHCID 67364627HCID 67364627—

Reaction Steps

The title compound is prepared analogously as described for GP1 using 5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2-(piperidin-4-yl)-2,4-dihydro-3H-pyrazol-3-one hydrochloride (compound B1*HCl) and 2,3-difluorobenzoyl chloride as starting compounds. The crude product is purified by crystallization from EA and diethyl ether to yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09340522B2
Source datasetuspto-grants-2016_05
ORD IDord-2b8ba2c568b34476b56097d1462fbf27
Source noteuspto-grants-2016_05