HCID 68182358, compound → HCID 68182478, compound

Participants

Reaction Steps

To a solution of tert-butyl 6-(3-nitropyrazol-1-yl)pyridine-3-carboxylate (0.505 gm, 1.74 mmol) in ethyl acetate (15 mL), 10% Pd/C (0.100 g, 20% w/w) was added under argon atmosphere. Argon gas was removed under vacuum and reaction flask was filled with hydrogen gas at 40 psi pressure. Reaction mixture was stirred for 1 hr on parr-apparatus. Reaction mixture was filtered through celite pad and concentrated under reduced pressure to give tert-butyl 6-(3-aminopyrazol-1-yl)pyridine-3-carboxylate (0.450 gm.)

Provenance & Evidence