反应详情

Ethyl 6-(bromomethyl)-4-(2-chloro-4-fluorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (0.18 g, 0.39 mmol) was reacted with 2-(morpholin-3-yl)acetic acid hydrochloride (0.07 g, 0.39 mmol) according to the procedure as described in Example 1, Step C to give the title compound as a light yellow solid (0.14 g, 67%). The compound was characterized by the following spectroscopic data: