Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Morpholine-3-carboxamide → HCID 73294951, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Morpholine-3-carboxamide | HCID 19792002 | — |
| 반응물 | Ethyl 6-(bromomethyl)-4-(2-chloro-4-fluorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate | HCID 118107632 | — |
| 생성물 | HCID 73294951 | HCID 73294951 | 45% |
반응 단계
Ethyl 6-(bromomethyl)-4-(2-chloro-4-fluorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (2.75 g, 6 mmol) was reacted with morpholine-3-carboxamide (0.78 g, 6 mmol) according to the procedure as described in Example 25, Step B to give the title compound as a yellow solid (1.37 g, 45%). The compound was characterized by the following spectroscopic data:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09340538B2 |
| 출처 데이터셋 | uspto-grants-2016_05 |
| ORD ID | ord-6cd242f4d92d49a4a53d64eab0a7040f |
| 출처 메모 | uspto-grants-2016_05 |