HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → (S)-benzyl 4-benzyl-2,2-dimethyl-5-oxomorpholine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | (S)-4-benzyl-2,2-dimethyl-5-oxomorpholine-3-carboxylic acid | HCID 90042977 | — |
| Product | (S)-benzyl 4-benzyl-2,2-dimethyl-5-oxomorpholine-3-carboxylate | HCID 118118261 | 54% |
Reaction Steps
(S)-4-benzyl-2,2-dimethyl-5-oxomorpholine-3-carboxylic acid (11.2 g, 42.5 mmol) was reacted with benzyl bromide (8.72 g, 51 mmol) according to the procedure as described in Example 34, Step A to give the title compound as a white solid (8.11 g, 54%). The compound was characterized by the following spectroscopic data:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09340538B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-a9d730edb01344c6aecdd428ae4aad0e |
| Source note | uspto-grants-2016_05 |