Acetic Acid → HCID 118107616, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of (S)-tert-butyl 3-((2-hydroxyethyl)carbamoyl)morpholine-4-carboxylate (0.33 g, 1.2 mmol) in glacial acetic acid (0.5 mL) was added a solution of HCl in EtOAc (6 mol/L, 15 mL), then the mixture was stirred closedly at 25° C. for 12 hours. The mixture was concentrated in vacuo to give the title compound as glutinous semisolid (0.21 g, 70%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence