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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 524652Generated: October 29, 2026

Isopropylamine → HCID 118107581, compound

https://huagongshe.com/reaction/524652

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropylamineHCID 6363—
Reactant2-(2-(4-(2-Bromo-4-fluorophenyl)-5-(ethoxycarbonyl)-6-methyl-1,4-dihydropyrimidin-2-yl)thiazol-4-yl)acetic acidHCID 118107631—
ProductHCID 118107581HCID 11810758145%

Reaction Steps

2-(2-(4-(2-bromo-4-fluorophenyl)-5-(ethoxycarbonyl)-6-methyl-1,4-dihydropyrimidin-2-yl)thiazol-4-yl)acetic acid (3 g, 6.2 mmol) was reacted with isopropylamine (0.55 g, 9.3 mmol) according to the procedure as described in Example 62, Step B to give the title compound as a yellow solid (1.46 g, 45%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09340538B2
Source datasetuspto-grants-2016_05
ORD IDord-422ba2ef9657409e883ec2972b247443
Source noteuspto-grants-2016_05