HCID 90043982, compound → HCID 90042788, compound

HRID 524660Notes

Reaction equation

HRID 524660 reaction equation
C([N:8]1[CH2:13][CH2:12][O:11][CH2:10][CH:9]1[CH2:14][CH:15]([C:21]([O:23][CH2:24][CH3:25])=[O:22])[C:16]([O:18][CH2:19][CH3:20])=[O:17])C1C=CC=CC=1>[Pd]>[NH:8]1[CH2:13][CH2:12][O:11][CH2:10][CH:9]1[CH2:14][CH:15]([C:21]([O:23][CH2:24][CH3:25])=[O:22])[C:16]([O:18][CH2:19][CH3:20])=[O:17]

Participants

3

Reactant 1

HCID 90043982HCID 90043982, compound

Product 1

HCID 90042788HCID 90042788, compoundYield 89%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Diethyl 2-((4-benzylmorpholin-3-yl)methyl)malonate (1 g, 2.86 mmol) was reacted with Pd/C (10%, 0.1 g) according to the procedure as described in Example 34, Step C to give the title compound as colorless oil (0.66 g, 89%). The compound was characterized by the following spectroscopic data:

Sources & evidence

ORD record
ord-56b8a74550a24dafa2e46cdcbcd2104a
Source dataset
uspto-grants-2016_05
Patent number
US09340538B2

Reaction notes

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