HCID 90043292, compound → HCID 90043304, compound

HRID 524663Notes

Reaction equation

HRID 524663 reaction equation
C([N:8]1[CH2:13][CH2:12][O:11][CH2:10][CH:9]1[CH2:14][CH:15]([CH2:18][OH:19])[CH2:16][OH:17])C1C=CC=CC=1>[Pd]>[NH:8]1[CH2:13][CH2:12][O:11][CH2:10][CH:9]1[CH2:14][CH:15]([CH2:18][OH:19])[CH2:16][OH:17]

Participants

3

Reactant 1

HCID 90043292HCID 90043292, compound

Product 1

HCID 90043304HCID 90043304, compoundYield 83.9%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

2-((4-benzylmorpholin-3-yl)methyl)propane-1,3-diol (0.18 g, 0.68 mmol) was reacted with Pd/C (10%, 25 mg) according to the procedure as described in Example 34, Step C to give the title compound as colorless oil (0.1 g, 83%). The compound was characterized by the following spectroscopic data:

Sources & evidence

ORD record
ord-8c680e9441c34e47882fc521559d0bf3
Source dataset
uspto-grants-2016_05
Patent number
US09340538B2

Reaction notes

Loading…