Ethyl Acetoacetate → HCID 90043973, compound

Participants

Reaction Steps

5-methyl-1,3,4-thiadiazole-2-carboximidamide hydrochloride (1.8 g, 10 mmol) was reacted with 2-bromo-4-fluorobenzaldehyde (2.03 g, 10 mmol) and ethyl 3-oxobutanoate (1.56 g, 12 mmol) according to the procedure as described in Example 1, Step A to give the title compound as a yellow solid (1.0 g, 25%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence