Ammonium Chloride → HCID 90043256, compound

HRID 524669Notes

Reaction equation

[S:1]1[CH:5]=[N:4][N:3]=[C:2]1[C:6]#[N:7].C[O-].[Na+].[Cl-:11].[NH4+:12]>>[ClH:11].[S:1]1[CH:5]=[N:4][N:3]=[C:2]1[C:6](=[NH:12])[NH2:7]

Participants

Reactant 3

HCID 25517Ammonium Chloride

HCID 10942334Sodium Methoxide

HCID 18543932HCID 18543932, compound

Product 1

HCID 90043256HCID 90043256, compound

Procedure

1,3,4-thiadiazole-2-carbonitrile (1.11 g, 10 mmol) was reacted with sodium methoxide (0.81 g, 15 mmol) and ammonium chloride (0.96 g, 18 mmol) according to the procedure as described in Example 61, Step B to give the title compound as an offwhite solid (1.15 g, 70%). The compound was characterized by the following spectroscopic data:

Sources & evidence

ORD record: ord-224397c2a4d143bf996f6aeb2d772e35
Source dataset: uspto-grants-2016_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09340538B2

Reaction notes

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