Ethyl Acetoacetate → HCID 90042808, compound

Participants

Reaction Steps

1,3,4-thiadiazole-2-carboximidamide hydrochloride (1.43 g, 8.69 mmol) was reacted with 2-chloro-4-fluorobenzaldehyde (1.38 g, 8.69 mmol) and ethyl 3-oxobutanoate (1.36 g, 10.5 mmol) according to the procedure as described in Example 1, Step A to give the title compound as a yellow solid (1.82 g, 55%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence