3-Morpholinecarboxylic acid → HCID 90044025, compound

Participants

Reaction Steps

Ethyl 6-(bromomethyl)-4-(2-chloro-4-fluorophenyl)-2-(1,3,4-thiadiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (0.69 g, 1.5 mmol) was reacted with morpholine-3-carboxylic acid (0.2 g, 1.5 mmol) according to the procedure as described in Example 1, Step C to give the title compound as a yellow solid (0.47 g, 61%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence