N-bromobutanimide → HCID 118107627, compound

Participants

Reaction Steps

Ethyl 4-(2,4-difluorophenyl)-6-methyl-2-(1,3,4-thiadiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (0.73 g, 2 mmol) was reacted with NBS (0.36 g, 2 mmol) according to the procedure as described in Example 1, Step B to give the title compound as a yellow solid (0.53 g, 60%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence