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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 524686Generated: October 29, 2026

HCID 90043354, compound → HCID 118107597, compound

https://huagongshe.com/reaction/524686

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 90043354HCID 90043354—
ReactantEthyl 6-(bromomethyl)-4-(2,4-dichlorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylateHCID 118107510—
ProductHCID 118107597HCID 11810759763.1%

Reaction Steps

Ethyl 6-(bromomethyl)-4-(2,4-dichlorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (2.38 g, 5 mmol) was reacted with isopropyl morpholine-3-carboxylate hydrochloride (1.05 g, 5 mmol) according to the procedure as described in Example 24 to give the title compound as a yellow solid (1.79 g, 63%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09340538B2
Source datasetuspto-grants-2016_05
ORD IDord-0b9dcafc1c3c4dc08993512914547100
Source noteuspto-grants-2016_05