HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 90043354, compound → HCID 118107597, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 90043354 | HCID 90043354 | — |
| Reactant | Ethyl 6-(bromomethyl)-4-(2,4-dichlorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate | HCID 118107510 | — |
| Product | HCID 118107597 | HCID 118107597 | 63.1% |
Reaction Steps
Ethyl 6-(bromomethyl)-4-(2,4-dichlorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (2.38 g, 5 mmol) was reacted with isopropyl morpholine-3-carboxylate hydrochloride (1.05 g, 5 mmol) according to the procedure as described in Example 24 to give the title compound as a yellow solid (1.79 g, 63%). The compound was characterized by the following spectroscopic data:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09340538B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-0b9dcafc1c3c4dc08993512914547100 |
| Source note | uspto-grants-2016_05 |