反应详情

Ethyl 4-(2-bromo-4-fluorophenyl)-6-(bromomethyl)-2-(1H-1,2,4-triazol-1-yl)-1,4-dihydropyrimidine-5-carboxylate (1.75 g, 3.6 mmol) was reacted with morpholine-3-carboxylic acid hydrochloride (0.6 g, 3.6 mmol) according to the procedure as described in Example 1, Step C to give the title compound as a pale yellow solid (0.6 g, 31%). The compound was characterized by the following spectroscopic data: