3-Morpholinecarboxylic acid → HCID 73296879, compound

Participants

Reaction Steps

Ethyl 4-(2-bromo-4-fluorophenyl)-6-(bromomethyl)-2-(furan-2-yl)-1,4-dihydropyrimidine-5-carboxylate (0.74 g, 1.53 mmol) (The compound was synthesized according to the procedure as described in WO2010069147) was reacted with morpholine-3-carboxylic acid (0.2 g, 1.53 mmol) according to the procedure as described in Example 28 to give the title compound as a yellow solid (0.31 g, 38%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence