N-bromobutanimide → HCID 118107585, compound

Participants

Reaction Steps

Ethyl 4-(2-bromo-4-fluorophenyl)-6-methyl-2-(oxazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (5.47 g, 13.4 mmol) was reacted with NBS (2.87 g, 16.1 mmol) according to the procedure as described in Example 1, Step B to give the title compound as a yellow solid (3.3 g, 51%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence