HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 90043196, compound → HCID 73296877, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 90043196 | HCID 90043196 | — |
| Reactant | Ethyl 6-(bromomethyl)-4-(2,4-dichlorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate | HCID 118107510 | — |
| Product | HCID 73296877 | HCID 73296877 | 40.2% |
Reaction Steps
Ethyl 6-(bromomethyl)-4-(2,4-dichlorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (0.73 g, 1.53 mmol) was reacted with 2-(morpholin-3-yl)propanoic acid hydrochloride (0.3 g, 1.53 mmol) according to the procedure as described in Example 28 to give the title compound as a yellow solid (0.34 g, 40%). The compound was characterized by the following spectroscopic data:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09340538B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-c0039ffc469c455fbe2c2fe601ed1ca1 |
| Source note | uspto-grants-2016_05 |