N-bromobutanimide → HCID 118107555, compound

Participants

Reaction Steps

Ethyl 4-(2-bromo-4-fluorophenyl)-2-(5-fluorothiazol-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate (0.51 g, 1.16 mmol) was reacted with NBS (0.21 g, 1.16 mmol) according to the procedure as described in Example 1, Step B to give the title compound as a yellow solid (0.52 g, 86%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence