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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 524769Generated: October 30, 2026

Ethyl Acetoacetate → HCID 90042425, compound

https://huagongshe.com/reaction/524769

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetoacetateHCID 8868—
Reactant2-Chloro-4-fluorobenzaldehydeHCID 145024—
ReactantHCID 90043393HCID 90043393—
ProductHCID 90042425HCID 9004242539.9%

Reaction Steps

5-fluorothiazole-2-carboximidamide acetate (0.22 g, 1.07 mmol) was reacted with 2-chloro-4-fluorobenzaldehyde (0.17 g, 1.07 mmol) and ethyl 3-oxobutanoate (0.14 g, 1.07 mmol) according to the procedure as described in Example 1, Step A to give the title compound as a yellow solid (0.17 g, 39%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09340538B2
Source datasetuspto-grants-2016_05
ORD IDord-7e300708331847469042f349891bfdab
Source noteuspto-grants-2016_05