4-Methylpiperazine-2-carboxylic acid → HCID 73296578, compound

Participants

Reaction Steps

Ethyl 4-(2-bromo-4-fluorophenyl)-6-(bromomethyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (1.5 g, 3 mmol) was reacted with 4-methylpiperazine-2-carboxylic acid (0.43 g, 3 mmol) according to the procedure as described in Example 1, Step C to give the title compound as a yellow solid (1.00 g, 59%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence