Sodium Hydroxide → HCID 131735583, compound

HRID 524787Notes

Reaction equation

HRID 524787 reaction equation
C[O:2][C:3](=[O:22])[CH:4]=[CH:5][CH:6]1[O:11][CH2:10][CH2:9][N:8]([C:12]([O:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[O:13])[CH2:7]1.[OH-].[Na+]>>[CH2:15]([O:14][C:12]([N:8]1[CH2:9][CH2:10][O:11][CH:6]([CH:5]=[CH:4][C:3]([OH:22])=[O:2])[CH2:7]1)=[O:13])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 131735582HCID 131735582, compound

Product 1

HCID 131735583HCID 131735583, compoundYield 96.2%

Procedure

Benzyl 2-(3-methoxy-3-oxoprop-1-en-1-yl)morpholine-4-carboxylate (0.86 g, 2.82 mmol) was reacted with NaOH (1.12 g, 28.2 mmol) according to the procedure as described in Example 21, Step A to give the title compound as colorless oil (0.79 g, 96%). The compound was characterized by the following spectroscopic data:

Sources & evidence

ORD record
ord-50ee5169a17f4f70a095e0419d821db7
Source dataset
uspto-grants-2016_05
Patent number
US09340538B2

Reaction notes

Loading…