HCID 131735583, compound → HCID 18784425, compound

HRID 524788Notes

Reaction equation

HRID 524788 reaction equation
C(OC([N:11]1[CH2:16][CH2:15][O:14][CH:13]([CH:17]=[CH:18][C:19]([OH:21])=[O:20])[CH2:12]1)=O)C1C=CC=CC=1>[Pd]>[NH:11]1[CH2:16][CH2:15][O:14][CH:13]([CH2:17][CH2:18][C:19]([OH:21])=[O:20])[CH2:12]1

Participants

3

Reactant 1

HCID 131735583HCID 131735583, compound

Product 1

HCID 18784425HCID 18784425, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

3-(4-((benzyloxy)carbonyl)morpholin-2-yl)acrylic acid (0.52 g, 1.8 mmol) was reacted with Pd—C (10%, 0.05 g) according to the procedure as described in Example 34, Step C to give the title compound as a white solid (0.2 g, 70%). The compound was characterized by the following spectroscopic data:

Sources & evidence

ORD record
ord-7f42e42bac4144709dee11fc93f5e0bb
Source dataset
uspto-grants-2016_05
Patent number
US09340538B2

Reaction notes

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