Aluminium lithium hydride → HCID 21183377, compound

HRID 524794Notes

Reaction equation

HRID 524794 reaction equation
[NH:1]1[CH2:6][CH2:5][O:4][CH:3]([CH2:7][CH2:8][C:9](OC)=[O:10])[CH2:2]1.[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[NH:1]1[CH2:6][CH2:5][O:4][CH:3]([CH2:7][CH2:8][CH2:9][OH:10])[CH2:2]1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 84065206HCID 84065206, compound

Product 1

HCID 21183377HCID 21183377, compoundYield 75%

Procedure

Methyl 3-(morpholin-2-yl)propanoate (0.69 g, 4 mmol) was reacted with LiAlH4 (0.23 g, 6 mmol) according to the procedure as described in Example 68, Step A to give the title compound as colorless oil (0.43 g, 75%). The compound was characterized by the following spectroscopic data:

Sources & evidence

ORD record
ord-696498e7d7244fc7934012c4621a445b
Source dataset
uspto-grants-2016_05
Patent number
US09340538B2

Reaction notes

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