Aniline → 4778-75-0

HRID 524976Notes

Reaction equation

HRID 524976 reaction equation
[NH:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([OH:8])=O.[NH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[C:10]1([NH:9][C:6]([C:2]2[NH:1][CH:5]=[CH:4][CH:3]=2)=[O:8])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 6115AnilineHCID 12473Pyrrole-2-Carboxylic Acid

Product 1

HCID 8997744778-75-0Yield 78%

Procedure

Prepared following the experimental method described in preparation 1a starting from 10.0 g (90.0 mmol) of 1H-pyrrole-2-carboxylic acid (purchased from Aldrich®, cat. no. P7,360-9) and 9.22 g (99.0 mmol) of aniline. 13.0 g (78% yield) of the title compound were obtained as a brownish solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-68ab6ed108ec4dd68b685f6415dc151e
Source dataset
uspto-grants-2016_05
Patent number
US09340547B2

Reaction notes

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