HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → 3-methyl-N-phenyl-1H-pyrrole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | 3-methyl-1H-pyrrole-2-carboxylic acid | HCID 7140352 | — |
| Product | 3-methyl-N-phenyl-1H-pyrrole-2-carboxamide | HCID 70922362 | 49% |
Reaction Steps
Prepared following the experimental method described in preparation 1a starting from 1.38 g (11.3 mmol) of 3-methyl-1H-pyrrole-2-carboxylic acid and 1.13 g (12.13 mmol) of aniline. After purification by flash chromatography (0-40% AcOEt in hexane), 1.08 g (49% yield) of the title compound were obtained as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09340547B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-9e5f14d29e6d4c799c80836d2f3df2fc |
| Source note | uspto-grants-2016_05 |