Hydrochloric Acid → HCID 73443115, compound

Participants

Reaction Steps

To a solution of methyl-{(S)-1-[(S)-2-methyl-1-((S)-2-phenylaminomethyl-2,3-dihydro-pyrrolo[2,3-b]pyridine-1-carbonyl)-propylcarbamoyl]-ethyl}-carbamic acid tert-butyl ester (25 mg, 0.05 mmol) in 1,4-dioxane (0.5 mL) was added 4 M HCl in dioxane (0.5 mL) dropwise at 0° C. The reaction mixture was stirred at rt for 3 h then concentrated in vacuo to obtain (S)-2-methylamino-N—[(S)-2-methyl-1-((S)-2-phenylaminomethyl-2,3-dihydro-pyrrolo[2,3-b]pyridine-1-carbonyl)-propyl]-propionamide hydrochloride (18 mg), m/z=410.4 (M+H).

Provenance & Evidence