HCID 178445718, compound → 6-Bromo-2-(4-tert-butyl-cyclohexyloxy)-quinoline

HRID 525449Notes

Reaction equation

HRID 525449 reaction equation
[Br:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([O:12][C@H:13]3[CH2:18][CH2:17][C@H:16]([C:19]([CH3:22])([CH3:21])[CH3:20])[CH2:15][CH2:14]3)C=2)[CH:3]=1.BrC1C=C2C(=CC=1)[N:30]=C(O)C=C2>>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:30]=[C:7]([O:12][CH:13]1[CH2:18][CH2:17][CH:16]([C:19]([CH3:22])([CH3:21])[CH3:20])[CH2:15][CH2:14]1)[CH:6]=[CH:5]2

Participants

3

Reactant 2

HCID 178445718HCID 178445718, compoundHCID 178515482HCID 178515482, compound

Product 1

HCID 669265836-Bromo-2-(4-tert-butyl-cyclohexyloxy)-quinoline

Procedure

Synthesized as per 2-bromo-6-(trans-4-tert-butylcyclohexyloxy)naphthalene using 6-Bromo-quinolin-2-ol as starting material. ESI-MS (M+H+): 362.1/364.10).

Sources & evidence

ORD record
ord-fe1c1e8550dc4f9e9524af0538cf1b97
Source dataset
uspto-grants-2016_05
Patent number
US09340527B2

Reaction notes

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