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HRID525580

反应详情

EQUATION

反应方程式

HRID 525580 的结构方程式

REACTANTS

反应物

2
结构：C#CCNS(C)(=O)=O
HCID14025440

N-(Prop-2-yn-1-yl)methanesulfonamide

C4H7NO2S

结构：[N-]=[N+]=Nc1ccc([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)cc1
HCID86695459

未命名化合物

PRODUCTS

生成物

1
结构：CS(=O)(=O)NCc1cn(-c2ccc([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)cc2)nn1
HCID89790578

未命名化合物

PROCEDURE

实验过程

Following the general procedure of Example 66, Step 3 and making non-critical variations but using the product of step 1, Example 67 with the product of Example 66, Step 2 the title compound is obtained (45 mg). 1H-NMR (400 MHz, DMSO-d6) δ: 2.95 (s, 3H), 4.25-4.26 (m, 1H), 4.30 (s, 2H), 4.33-4.34 (m, 0.5H), 4.42-4.46 (m, 0.5H), 4.58-4.61 (m, 0.5H), 4.69-4.73 (m, 0.5H), 4.95 (t, 1H, J=3.3 Hz), 6.08 (d, 1H, J=3.92 Hz), 6.49 (s, 1H), 7.55 (d, 2H, J=8.56 Hz), 7.84 (d, 2H, J=8.6 Hz), 8.64 (d, 1H, J=9.04 Hz), 8.70 (s, 1H). LC-MS (m/z): [M+H]=453.9.