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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 52582Generated: October 25, 2026

Diphenylacetic Acid → (R)-N5-[Amino(nitroimino) methyl]-N2-(diphenylacetyl)-N-[[4-(hydroxymethyl)-phenyl]methyl]-ornithinamide

https://huagongshe.com/reaction/52582

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
Reactant(R)-N5-[amino(nitroimino)methyl]-N-[[4-(hydroxymethyl)phenyl]methyl]-ornithinamideHCID 136381096—
Product(R)-N5-[Amino(nitroimino) methyl]-N2-(diphenylacetyl)-N-[[4-(hydroxymethyl)-phenyl]methyl]-ornithinamideHCID 13638109879%

Reaction Steps

Prepared analogously to Example 5f) from (R)-N5 -[amino(nitroimino)methyl]-N-[[4-(hydroxymethyl)phenyl]methyl]-ornithinamide, diphenylacetic acid and TBTU in a yield of 79% of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616620
Source datasetuspto-grants-1997_04
ORD IDord-51ecce6d508c4e8dacb4d5a3b4e64aac
Source noteuspto-grants-1997_04