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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 52586Generated: October 25, 2026

Phenylacetic Acid → (R)-N5-(Amino(nitroimino)methyl]-N-[(4-hydroxyphenyl)methyl]-N2-(phenylacetyl)-ornithinamide

https://huagongshe.com/reaction/52586

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylacetic AcidHCID 999—
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
Reactant(R)-N5-[amino(nitroimino)methyl]-N-[(4-hydroxyphenyl)methyl)-ornithinamideHCID 136381090—
Product(R)-N5-(Amino(nitroimino)methyl]-N-[(4-hydroxyphenyl)methyl]-N2-(phenylacetyl)-ornithinamideHCID 13638110261%

Reaction Steps

Prepared analogously to Example 5f) from (R)-N5 -[amino (nitroimino) methyl]-N-[(4-hydroxyphenyl) methyl]ornithinamide, phenylacetic acid and TBTU in a yield of 61% of theory. It was further processed without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616620
Source datasetuspto-grants-1997_04
ORD IDord-48263591402d49cfbc2c7df15a519c5e
Source noteuspto-grants-1997_04