tert-Butanol → HCID 178457539, compound

Participants

Reaction Steps

To a solution of N,N′-methanediylidenebis(propan-2-amine) (307 ml, 1981 mmol) in t-BuOH (227 ml, 2377 mmol) at r.t. was added copper(I) chloride (1.961 g, 19.81 mmol). The reaction was stirred at room temperature for 24 h and the resulting mixture was distilled under reduced pressure to afford (E)-tert-butyl N,N′-diisopropylcarbamimidate (279 g, 1393 mmol, 70.3% yield) as a colorless liquid. 1H NMR (400 MHz, CHLOROFORM-d4) δ ppm 1.04 (d, J=−6.06 Hz, 6 H) 1.08 (d, J=6.57 Hz, 6 H) 1.46 (s, 9 H) 2.98-3.19 (m, 1 H) 3.25 (m, 1 H) 3.64 (s, 1 H)

Provenance & Evidence