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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 52595Generated: October 26, 2026

O-Methyltyramine → N5-[Amino(nitroimino)methyl]-N2-(diphenylacetyl)-N-[2-(4-methoxyphenyl)ethyl]-ornithinamide

https://huagongshe.com/reaction/52595

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-MethyltyramineHCID 4657—
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
Reactant(R)-N5-[amino(nitroimino)methyl]-N2-(diphenylacetyl)-ornithineHCID 136381100—
ProductN5-[Amino(nitroimino)methyl]-N2-(diphenylacetyl)-N-[2-(4-methoxyphenyl)ethyl]-ornithinamideHCID 13638111347%

Reaction Steps

Prepared analogously to Example 8a) from (R)-N5 -[amino(nitroimino)methyl]-N2 -(diphenylacetyl)-ornithine, 4-methoxybenzenethanamine and TBTU in a yield of 47% of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616620
Source datasetuspto-grants-1997_04
ORD IDord-e9a0414aba054e69bac783df1acedb20
Source noteuspto-grants-1997_04