HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 178476430, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | HCID 137231658 | HCID 137231658 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178476430 | HCID 178476430 | 97% |
Reaction Steps
Prepared analogously to Example 1c) from (R)-N5 -[amino(nitroimino)methyl]-N2 -(diphenylacetyl)-N-[(4-ethoxyphenyl)-methyl]-ornithinamide by catalytic hydrogenation in the presence of palladium black and 80% aqueous acetic acid in a yield of 97% of theory. Colourless crystals, mp. 97°-100° C. and Rf 0.75. IR (CH2Cl2): 1665 cm-1 (C=O) 1515 cm-1 (amide-II) ESI-MS: (M+H)+ =502
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05616620 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-0e862e44f6e74abea5a6d656f910cb72 |
| Source note | uspto-grants-1997_04 |