HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57582496, compound → HCID 15980988, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57582496 | HCID 57582496 | — |
| Solvent | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Product | HCID 15980988 | HCID 15980988 | 45.1% |
Reaction Steps
2-(4-Acetamidophenyl)-2-methoxyacetic acid (7.1 g, 31.8 mmol) was heated with hydrazine monohydrate (40 ml) for 16 hr, cooled and concentrated in vacuo. The resulting residual oil was purified by silica gel column chromatography (eluent 20-40% methanol in CH2Cl2) to give 2.6 g (45%) of (±)-2-methoxy-2-(4′-aminophenyl)-acetic acid
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09345680B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-7be30431c0674a748512d063e199a60a |
| Source note | uspto-grants-2016_05 |