HCID 57582487, compound → HCID 15980990, compound

Participants

Reaction Steps

2-Ethoxy-2-(3-nitrophenyl)acetic acid (6.4 g, 28.4 mmol) was dissolved in absolute ethanol (500 ml), 5% palladium on carbon (wet) (1.5 g) added and the mixture hydrogenated at 60 psi overnight. The suspension was filtered through celite and the filtrate concentrated to give (±)-2-ethoxy-2-(3′-aminophenyl)-acetic acid (3.0 g, 15.3 mmol, 54%) as a brown solid.

Provenance & Evidence